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Agent-based models in Cellular Systems

Jonas and Christian publish a mini-review about the current state of agent-based models with special emphasis on their usage in modeling cellular systems.

Agent-based models in Cellular Systems

Find the full text on frontiersin.org/ or via doi.org/10.3389/fphy.2022.968409.

This mini-review discusses agent-based models as modeling techniques for studying pattern formation of multi-cellular systems in biology. We introduce and compare different agent-based model frameworks with respect to spatial representation, microenvironment, intracellular and extracellular reactions, cellular properties, implementation, and practical use. The guiding criteria for the considered selection of agent-based model frameworks are that they are actively maintained, well documented, and provide a model development workflow.